Study: The right time for physical activity increases fat metabolism

Solna [Sweden]February 18 (ANI): According to a recent study from Sweden's Karolinska Institute and Denmark's University of Copenhagen, mice that exercised during an early active phase, which is comparable to morning exercise in humans, had higher metabolic rates than mice that exercised during a time when they usually rested.

The results of the study were published in the journal PNAS.

Physical activity at different times of the day can affect the body in different ways because the biological processes depend on the circadian rhythm of the cells. To determine how the time of day when the exercise is done affects fat burning, researchers at the Karolinska Institutet and the University of Copenhagen studied the adipose tissue of mice after a session of high-intensity exercise performed at two points in the daily cycle. an early active phase and early resting phase (equivalent to late morning and late evening sessions in humans). The researchers studied various markers for fat metabolism and analyzed which genes were active in the adipose tissue after exercise.

Independent of food intake, the researchers found that physical activity in an early active phase increased the expression of genes involved in the breakdown of adipose tissue, thermogenesis (heat production) and mitochondria in the adipose tissue, indicating a higher metabolic rate. These effects were observed only in mice exercising in the early active phase and were independent of food intake.

"Our findings suggest that late morning exercise may be more effective than late evening exercise in increasing metabolism and burning fat, and if so may prove to be of value to people who are overweight," said Professor Juleen R. Zierath from the Department of Molecular Medicine and Surgery and the Department of Physiology and Pharmacology, Karolinska Institutet.

Improve health exercise">the benefits of exercise Mice and humans share many basic physiological functions, and mice are a well-established model for human physiology and metabolism. But there are also important differences, such as the fact that mice are nocturnal.

"Proper timing appears to be important for the body's energy balance and for improving the health benefits of exercise, but more studies are needed to draw any reliable conclusions about the relevance of our findings to humans," said Professor Zierath. (ANI)

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